Publications & projects

Recent research

Selected recent work from the Paris HLA Team on HLA immunogenetics, antibody characterisation and histocompatibility in transplantation.

Optimizing risk-benefit in highly sensitized kidney recipient antigen delisting increasing donor access

Usureau C, Siemowski J, Anglicheau D, Leon J, Matignon M, … Letort V, Taupin J-L. Kidney International · 2026

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Characterisation of the novel HLA-B*52:131 allele by sequencing-based typing

Le Mene M, Da Silva S, Le Collonnier AF, Taupin J-L. HLA · 2026

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Partial endothelial-to-mesenchymal transition precedes de novo donor-specific anti-HLA antibodies in kidney recipients experiencing delayed graft function

Xu-Dubois YC, Taupin J-L, Dao M, Luque Y, … Devriese M, … Hertig A. American Journal of Transplantation · 2026

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Biological effects of F(ab')2 fragments generated by imlifidase from anti-HLA IgG antibodies from transplant patients

Devriese M, Carelli I, Giraldo L, Pin A, Groshaeny N, Silva SD, Bockermann R, Taupin J-L. HLA · 2025

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Harnessing HLA divergence for improved donor selection in haploidentical haematopoietic stem cell transplantation

Jorge Cordeiro D, Villemonteix J, Xhaard A, … Caillat-Zucman S, Allain V. HLA · 2025

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The hunt for HLA-DQ allogeneic eplets is not over: four new ones, including a cross-chain eplet

Devriese M, Amaya-Ramirez D, Meng T, … Usureau C, Toutirais O, Smaïl-Tabbone M, Lowe D, Taupin J-L. HLA · 2025

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Characterisation of the novel HLA-C*14:168 allele by two different sequencing-based typing techniques

Devriese M, Le Collonnier AF, Le Mene M, Taupin J-L. HLA · 2025

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Characterisation of a novel HLA-C allele, HLA-C*08:307N

Devriese M, Le Collonnier AF, Carmagnat M, Toullec L, Taupin J-L. HLA · 2025

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Characterisation of the novel HLA-A*68:326 and -C*02:254N alleles by two different sequencing-based typing techniques

Le Mene M, Da Silva S, Le Collonnier AF, Devriese M, Taupin J-L. HLA · 2025

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Evaluating the antigen and eplet accuracy of DQA1 imputations with the HaploSFHI two-field HLA typing inference tool

Lhotte R, Murphey C, Tafulo S, Turner D, Usureau C, Devriese M, Letort V, Taupin J-L. HLA · 2025

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Donor HLA-DQ genetic and functional divergence affect the control of BK polyoma virus infection after kidney transplantation

Chevalier MF, Allain V, … Villemonteix J, … Taupin J-L, … Caillat-Zucman S. Science Advances · 2025

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HLA evolutionary divergence score after donor lymphocyte infusion following allogeneic hematopoietic stem cell transplantation

Le Grand S, Villemonteix J, Daguindau E, … Michonneau D, Guenounou S, Huynh A. HemaSphere · 2025

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HLA evolutionary divergence effect on bacterial infection risk in cirrhotic liver transplant candidates

Mazzola A, Roger C, Lhotte R, Mallet M, Thabut D, Taupin J-L, Conti F. Clinical Immunology · 2025

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HLA-EpiCheck: novel approach for HLA B-cell epitope prediction using 3D-surface patch descriptors derived from molecular dynamic simulations

Amaya-Ramirez D, Devriese M, Lhotte R, Usureau C, Smaïl-Tabbone M, Taupin J-L, Devignes M-D. Bioinformatics Advances · 2024

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The impact of HLA-A29 homozygosity and of the second HLA-A allele on susceptibility and severity of Birdshot chorioretinitis

Loeliger J, Lhotte R, Gelfman S, … Taupin J-L, … Brézin AP. Investigative Ophthalmology & Visual Science · 2024

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Characterisation of the HLA-DQ alpha eplet 52SK targeting the DQA1*01 alleles family

Devriese M, Lee JH, Meng T, … Usureau C, Toutirais O, Lowe D, Taupin J-L. HLA · 2024

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Refining cPRA calculation to improve HLA compatibility assessment in organ transplantation: a detailed picture of the Paris waiting list

Usureau C, Lhotte R, Clichet V, Foroutan A, Devriese M, Taupin J-L. HLA · 2024

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Bead-by-bead normalization of single antigen assays: a necessary step for accurate detection of weak anti-HLA antibodies

Usureau C, Lhotte R, Devriese M, Siemowski J, Gabet L, Letort V, Taupin J-L. European Journal of Immunology · 2024

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Donor-specific antibodies targeting a repeated eplet mismatch and outcome after kidney retransplantation

Arches C, Usureau C, Anglicheau D, Hertig A, Jalal-Eddine A, Zaidan M, Taupin J-L, Snanoudj R. Transplant International · 2024

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Separating the wheat from the chaff among HLA-DQ eplets

Devriese M, Lemonnier FA, Lion J, … Usureau C, Miyadera H, Toutirais O, Mooney N, Lowe D, Taupin J-L. Journal of Immunology · 2024

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Improving HLA typing imputation accuracy and eplet identification with local next-generation sequencing training data

Lhotte R, Letort V, Usureau C, Jorge-Cordeiro D, Siemowski J, Gabet L, Cournède PH, Taupin J-L. HLA · 2024

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Single-locus HLA sequencing with the nanopore technology for HLA disease-association diagnosis

Devriese M, Rouquie J, Da Silva S, … Caillat-Zucman S, Werner G, Taupin J-L. HLA · 2024

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Two-field resolution on-call HLA typing for deceased donors using nanopore sequencing

Devriese M, Da Silva S, Le Mene M, … Usureau C, … Werner G, Taupin J-L. HLA · 2024

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Multicentre and collaborative studies the team contributed to.

Anti-HLA antibodies and risk of fetal growth restriction

Hannoun P, Verdoux M, Jollet I, Taupin J-L, Zuber J, … Lafarge X. American Journal of Obstetrics & Gynecology · 2026

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B-cell maturation antigen-targeted T-cell engager therapy combined with B-cell depletion for treatment of refractory HLA sensitization

Leon J, Aubert O, Devriese M, … Usureau C, … Taupin J-L, … Zuber J. Kidney International · 2026

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Biointegration of a partially decellularized tracheal scaffold in a porcine model — preliminary results

Vigouroux A, Bonnin Y, Gendron N, … Devriese M, … Thierry B. Scientific Reports · 2026

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Immune tolerance breakdown in pregnancy: transplantation parallels in chronic intervillositis and villitis of unknown etiology

Hannoun P, Rabant M, Usureau C, Taupin J-L, Zuber J, Benachi A. American Journal of Obstetrics & Gynecology · 2026

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Skewed pretransplant lymphocyte subpopulations correlate with opportunistic infection onset within the first two years following kidney transplantation

Beldi-Ferchiou A, Runyo F, Canoui-Poitrine F, … Usureau C, … Matignon M. Frontiers in Immunology · 2025

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Low cystatin C-to-creatinine estimated GFR ratio predicts post-kidney-transplant cardiovascular events

Moryoussef M, Morel A, Zaidan L, … Usureau C, … Stehlé T. Kidney International Reports · 2025

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Perioperative C1-esterase inhibitor therapy to allow transplantation in a highly sensitized lung transplant candidate: three case reports

Devaquet J, Coiffard B, Demant X, Parquin F, Devriese M, … Roux A. American Journal of Transplantation · 2025

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Anti-HLA serologic response to CD38-targeting desensitization therapy is challenged by peripheral memory B cells in highly sensitized kidney transplant candidates

Torija A, Matignon M, Vincenti F, … Usureau C, … Grimbert P, Bestard O. American Journal of Transplantation · 2025

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Open-label phase 1/2 study of daratumumab-based desensitization before kidney transplantation

Pilon C, Joher N, Usureau C, Boutin E, … Taupin J-L, … Matignon M. Kidney International Reports · 2024

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Imlifidase in highly sensitized kidney transplant recipients with a positive crossmatch against a deceased donor

Kamar N, Bertrand D, Caillard S, … Usureau C, Taupin J-L, … Couzi L. Kidney International Reports · 2024

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Allogeneic CD4 T cells sustain effective BK polyomavirus-specific CD8 T-cell response in kidney transplant recipients

Dekeyser M, de Goër de Herve MG, Hendel-Chavez H, Lhotte R, … Taupin J-L, … Durrbach A. Kidney International Reports · 2024

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HLA class I peptide polymorphisms contribute to class II DQβ0603:DQα0103 antibody specificity

Shih NR, Nong T, Murphey C, … Taupin J-L, Devriese M, … Lee JH. Nature Communications · 2024

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